Antibody Discovery- In Vitro, Director, Global Biologics
Company: Takeda Pharmaceutical
Location: Boston
Posted on: October 30, 2024
Job Description:
By clicking the "Apply" button, I understand that my employment
application process with Takeda will commence and that the
information I provide in my application will be processed in line
with Takeda's and . I further attest that all information I submit
in my employment application is true to the best of my
knowledge.Job DescriptionAbout the role:At Takeda, we are a
forward-looking, world-class R&D organization that unlocks
innovation and delivers transformative therapies to patients. By
focusing R&D efforts on four therapeutic areas and other
targeted investments, we push the boundaries of what is possible in
order to bring life-changing therapies to patients worldwide.Join
Takeda as an Antibody Discovery- In Vitro, Director where you will
be an excellent addition to our fast paced and exciting team of
committed scientists, using your depth and breadth of knowledge in
the field of antibody discovery, optimization and progression of
programs forward through discovery towards IND. With your
experience and expertise in antibody discovery and optimization,
you will lead biologics programs from early discovery, through
candidate selection, to IND and be accountable for the performance
and results of a significant research function or activity that
incorporates in vitro based discovery platforms yeast and phage. As
part of the Biotherapeutic Engineering Team, you will report to the
Senior Director and work with the Global Biologics organization as
a leader who has accountability for the performance and results of
a significant research function or activity that incorporates in
vitro based discovery platforms yeast and phage.How you will
contribute:Scientific leader:
- Set high standards for effectiveness of execution, and rigor of
thought. Posses in-depth knowledge of antibody-based discovery,
optimization/ engineering using in vitro based discovery methods
such as yeast, phage, or mammalian display.
- Experience in appropriately mining and triaging of antibody
repertoires, to progress viable therapeutic molecules.
- Draw on expertise from in vitro based discovery platforms to
provide thoughtful guidance on strategies towards candidate
profiles for differing target types, optimization / engineering
approaches to enhance properties to progress from lead to
candidate.
- Incorporate NGS and Sanger based sequence analysis for both
repertoires and clonal populations.
- Identify and drive efficient paths for workflow
progression.
- Drive research strategy within the sub-team and foster
innovation.
- Contribute to deepening of the expertise through external
network development, evaluating new opportunities in partnership
with business development.Program Leader
- Lead biologics programs from discovery to IND, integrating
early research, progression through candidate nomination and
selection.
- Detailed knowledge of full biologics process from discovery to
pre-IND.
- Ambassador for the biologics department, scientifically
inputting to the project teams.
- Exceptionally collaborative mindset, working with internal
/external groups for high efficiency and transparency to enable
swift progression of molecules.People Leader
- Organizational leader accountable for the performance and
results of this significant research function with significant
managerial responsibility.
- Use enterprise mindset with a broad view across the portfolio
that informs resourcing and prioritization of programs under direct
remit.
- Empowerment to lead a small team of highly qualified and
skilled scientists in their mission to generate therapeutic
biologics.
- Develop the next generation of organizational and project
leaders, being a champion of new opportunities. Team-centric
mindset, inspiring and growing team members, while serving as a
role model and mentor.
- Responsible for effective resourcing within team to drive
programs forward in and efficient manner.
- Lead team through in-lab presence, designing and efficiently
executing discovery /optimization campaigns including affinity
maturation, developability; technology development.Other
- Excellent knowledge of data analysis tools to ensure thorough
evaluation of datasets and information based next step
decisions.
- High level of diligence in all data tracking, uploading, and
recording using data management systems within the department.
- Key involvement and due diligence for external interactions,
collaborations and workflows where appropriate.
- Contribute to the preparation of patents, documentation for
IND, and publications.Minimum Requirements/Qualifications:
- PhD degree in a scientific discipline with 10+ years experience
, or MS with 16+ years experience, or BS with 18+ years
experience.
- 9 years of Industry experience required.
- 9 years of managerial experience required.
- Outstanding expertise and depth of knowledge within a
scientific area.
- Keeps up with the up-to-date scientific advancement (e.g.
competitive landscape, new technology, new research portfolio, and
new partnership).
- Independently manages workload and expectations.
- Scientifically independent.
- Scientific driver for research strategy that impacts group
internally and outside area of function.More about us:At Takeda, we
are transforming patient care through the development of novel
specialty pharmaceuticals and best in class patient support
programs. Takeda is a patient-focused company that will inspire and
empower you to grow through life-changing work.Certified as a
Global Top Employer, Takeda offers stimulating careers, encourages
innovation, and strives for excellence in everything we do. We
foster an inclusive, collaborative workplace, in which our teams
are united by an unwavering commitment to deliver Better Health and
a Brighter Future to people around the
world.#LI-SGM#LI-OnsiteTakeda Compensation and Benefits SummaryWe
understand compensation is an important factor as you consider the
next step in your career. We are committed to equitable pay for all
employees, and we strive to be more transparent with our pay
practices. -For Location:Boston, MAU.S. Base Salary
Range:$169,400.00 - $266,200.00The estimated salary range reflects
an anticipated range for this position. The actual base salary
offered may depend on a variety of factors, including the
qualifications of the individual applicant for the position, years
of relevant experience, specific and unique skills, level of
education attained, certifications or other professional licenses
held, and the location in which the applicant lives and/or from
which they will be performing the job.---The actual base salary
offered will be in accordance with state or local minimum wage
requirements for the job location. -U.S. based employees may be
eligible for short-term and/ or long-term incentives. U.S. based
employees may be eligible to participate in medical, dental, vision
insurance, a 401(k) plan and company match, short-term and
long-term disability coverage, basic life insurance, a tuition
reimbursement program, paid volunteer time off, company holidays,
and well-being benefits, among others. U.S. based employees are
also eligible to receive, per calendar year, up to 80 hours of sick
time, and new hires are eligible to accrue up to 120 hours of paid
vacation. -EEO StatementTakeda is proud in its commitment to
creating a diverse workforce and providing equal employment
opportunities to all employees and applicants for employment
without regard to race, color, religion, sex, sexual orientation,
gender identity, gender expression, parental status, national
origin, age, disability, citizenship status, genetic information or
characteristics, marital status, status as a Vietnam era veteran,
special disabled veteran, or other protected veteran in accordance
with applicable federal, state and local laws, and any other
characteristic protected by law.LocationsBoston, MAWorker
TypeEmployeeWorker Sub-TypeRegularTime TypeFull time
Keywords: Takeda Pharmaceutical, Providence , Antibody Discovery- In Vitro, Director, Global Biologics, Executive , Boston, Rhode Island
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